Plant compounds
Spermidine
A substance from wheat germ, soy and aged cheese. Studied for how cells clean up worn-out parts and for healthy aging – mostly in animals.
15 products from US online stores, sorted by what 1 mg of spermidine costs – not by the price per pack.
$0.17Lowest cost
per 1 mg spermidine
- Prices checked Nov 1, 2026, US
- No paid placements

What does 1 mg mean?
- spermidine per serving in most of the products we checked
- 1–20 mgspermidine per serving in most of the products we checked
- 1 mg is a fixed amount to compare by: half of the 15 products we checked have up to 10 mg per serving, the other half more.
- There’s no official daily amount for spermidine.
We compare by 1 mg only so products line up – it’s not a recommendation. Not medical advice.
Where products miss quality points
How the 15 products score
- Very good 90+: 0
- Good 75+: 15
- Fair 60+: 0
- Low under 60: 0
- have no seal from an independent testing program
- 15 of 15have no seal from an independent testing program10 of 30 testing points for GMP, 15 for the 1 whose label says “third-party tested”
The full 30 testing points need an independent test. Every supplement sold in the US is made under the FDA’s GMP rules – the maker checks its own products, which gives 10 points. A seal from a testing program like NSF, USP or Informed Choice means a lab outside the company checks that what’s inside matches the label. Most brands don’t take part. That doesn’t make a product bad – without a seal, a clean product still gets up to 80.
We find seals on the label and in NSF’s public lists. USP and Informed Choice don’t let us search their lists automatically, so a seal that’s only in their lists can be missing. How the score works
Pack size
Compare packs of a similar size.
All sizes in one list can affect the results. Pick a size above to compare packs that are alike.
5 of 15 products · cheapest per 1 mg spermidine first
10 products are hidden
They have 10 mg spermidine or more in one serving – at least 10 times the 1 mg we compare. There’s no official upper limit, so we only mark them.
- Rank 1
ProHealth Longevity
Pure Spermidine, 1 mg
Capsules
75Good qualityCountry not stated$0.17per 1 mg
Lowest
- Pack
- $29.95180 capsules
- Spermidine per serving
- 1 mgin 1 capsule
- Pack lasts
- 180 daysif you take 1 capsule (1 mg) a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 2
ProHealth Longevity
Pure Spermidine - 1 mg
Capsules
75Good qualityCountry not stated$0.17per 1 mg
Lowest
- Pack
- $29.95180 capsules
- Spermidine per serving
- 1 mgin 1 capsule
- Pack lasts
- 180 daysif you take 1 capsule (1 mg) a day
prohealth.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 3
Solaray
Unlimit, Spermidine, 3.3 mg
Capsules
75Good qualityCountry not stated$0.20per 1 mg
22% more
- Pack
- $40.1060 capsules
- Spermidine per serving
- 3.3 mgin 1 capsule
- Pack lasts
- 60 daysif you take 1 capsule (3.3 mg) a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 4
California Gold Nutrition
Spermidine, Rice Germ Extract, 1 mg
Capsules
75Good qualityCountry not stated$0.29per 1 mg
72% more
- Pack
- $25.7690 capsules
- Spermidine per serving
- 1 mgin 1 capsule
- Pack lasts
- 90 daysif you take 1 capsule (1 mg) a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 5
California Gold Nutrition
Spermidine, Rice Germ Extract, 1 mg
Capsules
75Good qualityCountry not stated$0.36per 1 mg
116% more
- Pack
- $10.7930 capsules
- Spermidine per serving
- 1 mgin 1 capsule
- Pack lasts
- 30 daysif you take 1 capsule (1 mg) a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
Good to know
- Fact
- 116%more per 1 mg for the most expensive product than for the cheapest.
How we checked: one-time price for each size in the store’s US online shop, before sales tax and shipping, without subscriptions or coupons. Prices change often, so check the store before you buy. More on how we check
The amount we compare by only makes products comparable – it is not a dosage recommendation. Not medical advice.
How we calculate
Cost per dose = price ÷ (servings × amount per serving) × comparison amount. Example: $119.99 for 74 servings with 24 g of protein each is 1,776 g of protein. $119.99 ÷ 1,776 g × 30 g = $2.03 per 30 g of protein.
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