Collagen & connective tissue
MSM
A sulfur compound found in small amounts in food. Taken for joints – studies are small.
69 products from US online stores, sorted by what 1,000 mg of MSM costs – not by the price per pack.
3.2¢Lowest cost
per 1,000 mg MSM
- Prices checked Nov 1, 2026, US
- No paid placements
What does 1,000 mg mean?
- MSM per serving in most of the products we checked
- 1,000–3,000 mgMSM per serving in most of the products we checked
- 1,000 mg is about one serving: half of the 69 products we checked have up to 1,000 mg per serving, the other half more.
- There’s no official daily amount for MSM.
We compare by 1,000 mg only so products line up – it’s not a recommendation. Not medical advice.
Where products miss quality points
How the 69 products score
- Very good 90+: 0
- Good 75+: 69
- Fair 60+: 0
- Low under 60: 0
- have no seal from an independent testing program
- 100%have no seal from an independent testing program10 of 30 testing points for GMP, 15 for the 7 whose label says “third-party tested”
The full 30 testing points need an independent test. Every supplement sold in the US is made under the FDA’s GMP rules – the maker checks its own products, which gives 10 points. A seal from a testing program like NSF, USP or Informed Choice means a lab outside the company checks that what’s inside matches the label. Most brands don’t take part. That doesn’t make a product bad – without a seal, a clean product still gets up to 80.
We find seals on the label and in NSF’s public lists. USP and Informed Choice don’t let us search their lists automatically, so a seal that’s only in their lists can be missing. How the score works
Pack size
Compare packs of a similar size.
All sizes in one list can affect the results – big packs usually cost less per 1,000 mg. Pick a size above to compare packs that are alike.
69 products · cheapest per 1,000 mg MSM first
- Rank 1
Source Naturals
MSM Powder
Powder
80Good qualityCountry not stated3.2¢per 1,000 mg
Lowest
- Pack
- $30.781 kg (2.2 lb)400 servings
- MSM per serving
- 2,400 mgin 2.5 g
- Pack lasts
- 960 daysif you take 1,000 mg a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 2
NOW Foods
MSM Powder
Powder
80Good qualityCountry not stated3.5¢per 1,000 mg
9% more
- Pack
- $15.92454 g (1 lb)252 servings
- MSM per serving
- 1,800 mgin 1.8 g
- Pack lasts
- 454 daysif you take 1,000 mg a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 3
Nutricost
MSM, Unflavored
Powder
85Good qualityMade in USA3.6¢per 1,000 mg
11% more
- Pack
- $17.80500 g (1.1 lb)500 servings
- MSM per serving
- 1,000 mgin 1 g
- Pack lasts
- 500 daysif you take 1,000 mg a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 4
Emerald Laboratories
Vegan MSM Powder
Powder
80Good qualityCountry not stated3.8¢per 1,000 mg
17% more
- Pack
- $17.06454 g (1 lb)114 servings
- MSM per serving
- 4,000 mgin 4 g
- Pack lasts
- 454 daysif you take 1,000 mg a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 5
NOW Foods
MSM Powder
Powder
80Good qualityCountry not stated3.8¢per 1,000 mg
18% more
- Pack
- $8.56227 g (8 oz)126 servings
- MSM per serving
- 1,800 mgin 1.8 g
- Pack lasts
- 227 daysif you take 1,000 mg a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 6
Nutricost
MSM Powder
Powder
85Good qualityCountry not stated3.8¢per 1,000 mg
19% more
- Pack
- $18.97499 g (1.1 lb)499 servings
- MSM per serving
- 1,000 mgin 1 g
- Pack lasts
- 499 daysif you take 1,000 mg a day
nutricost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 7
Source Naturals
MSM Powder
Powder
80Good qualityCountry not stated3.8¢per 1,000 mg
20% more
- Pack
- $16.74454 g (1 lb)181 servings
- MSM per serving
- 2,400 mgin 2.5 g
- Pack lasts
- 435 daysif you take 1,000 mg a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 8
Swanson Vitamins
MSM Powder - Ready-Mix & Unflavored
Powder
80Good qualityCountry not stated4.6¢per 1,000 mg
44% more
- Pack
- $20.99454 g (1 lb)91 servings
- MSM per serving
- 5,000 mgin 5 g
- Pack lasts
- 454 daysif you take 1,000 mg a day
swansonvitamins.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 9
Swanson Vitamins
MSM Powder, Ready-Mix & Unflavored
Powder
80Good qualityCountry not stated4.9¢per 1,000 mg
51% more
- Pack
- $22.04454 g (1 lb)91 servings
- MSM per serving
- 5,000 mgin 5 g
- Pack lasts
- 454 daysif you take 1,000 mg a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 10
California Gold Nutrition
OptiMSM Flakes
Powder
80Good qualityCountry not stated4.9¢per 1,000 mg
53% more
- Pack
- $48.62992 g (2.2 lb)331 servings
- MSM per serving
- 3,000 mgin 3 g
- Pack lasts
- 992 daysif you take 1,000 mg a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 11
Doctor's Best
MSM Powder with OptiMSM
Powder
80Good qualityCountry not stated6¢per 1,000 mg
87% more
- Pack
- $14.99250 g (8.8 oz)83 servings
- MSM per serving
- 3,000 mgin 3 g
- Pack lasts
- 250 daysif you take 1,000 mg a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 12
Doctor's Best
MSM Powder with OptiMSM
Powder
80Good qualityCountry not stated6¢per 1,000 mg
88% more
- Pack
- $14.99249 g (8.8 oz)83 servings
- MSM per serving
- 3,000 mgin 3 g
- Pack lasts
- 249 daysif you take 1,000 mg a day
drbvitamins.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 13
MRM Nutrition
MSM Crystals - Pure Crystalline Methylsulfonylmethane
Powder
80Good qualityCountry not stated6.2¢per 1,000 mg
93% more
- Pack
- $12.37200 g (7.1 oz)200 servings
- MSM per serving
- 1,000 mgin 1 g
- Pack lasts
- 200 daysif you take 1,000 mg a day
mrmnutrition.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 14
Amazing Nutrition
Amazing Formulas MSM
Tablets
80Good qualityMade in USA6.3¢per 1,000 mg
96% more
- Pack
- $16.99180 tablets
- MSM per serving
- 1,500 mgin 1 tablet
- Pack lasts
- 180 daysif you take 1 tablet (1,500 mg) a day
amazingnutrition.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 15
NOW Foods
MSM, 1,500 mg
Tablets
80Good qualityMade in USA6.7¢per 1,000 mg
110% more
- Pack
- $20.20200 tablets100 servings
- MSM per serving
- 3,000 mgin 2 tablets
- Pack lasts
- 200 daysif you take 1 tablet (1,500 mg) a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 16
Swanson Vitamins
MSM
Tablets
80Good qualityCountry not stated6.8¢per 1,000 mg
113% more
- Pack
- $12.29120 tablets60 servings
- MSM per serving
- 3,000 mgin 2 tablets
- Pack lasts
- 120 daysif you take 1 tablet (1,500 mg) a day
swansonvitamins.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 17
Swanson Vitamins
MSM, 1,500 mg
Tablets
80Good qualityCountry not stated7¢per 1,000 mg
119% more
- Pack
- $12.66120 tablets60 servings
- MSM per serving
- 3,000 mgin 2 tablets
- Pack lasts
- 120 daysif you take 1 tablet (1,500 mg) a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 18
Doctor's Best
MSM with OptiMSM
Capsules
80Good qualityCountry not stated7.2¢per 1,000 mg
125% more
- Pack
- $25.99360 capsules120 servings
- MSM per serving
- 3,000 mgin 3 capsules
- Pack lasts
- 360 daysif you take 1 capsule (1,000 mg) a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 19
Nutricost
MSM
Tablets
85Good qualityPacked in USA7.5¢per 1,000 mg
133% more
- Pack
- $17.95240 tablets120 servings
- MSM per serving
- 2,000 mgin 2 tablets
- Pack lasts
- 240 daysif you take 1 tablet (1,000 mg) a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 20
Doctor's Best
MSM with OptiMSM
Capsules
80Good qualityCountry not stated7.5¢per 1,000 mg
134% more
- Pack
- $26.99360 capsules120 servings
- MSM per serving
- 3,000 mgin 3 capsules
- Pack lasts
- 360 daysif you take 1 capsule (1,000 mg) a day
drbvitamins.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 21
Amazing Nutrition
Amazing Formulas MSM
Capsules
80Good qualityMade in USA7.6¢per 1,000 mg
137% more
- Pack
- $18.99250 capsules125 servings
- MSM per serving
- 2,000 mgin 2 capsules
- Pack lasts
- 250 daysif you take 1 capsule (1,000 mg) a day
amazingnutrition.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 22
MRM Nutrition
MSM Crystals
Powder
80Good qualityCountry not stated7.7¢per 1,000 mg
141% more
- Pack
- $15.44200 g (7.1 oz)200 servings
- MSM per serving
- 1,000 mgin 1 g
- Pack lasts
- 200 daysif you take 1,000 mg a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 23
Doctor's Best
MSM with OptiMSM, 1,500 mg
Tablets
80Good qualityCountry not stated7.8¢per 1,000 mg
142% more
- Pack
- $13.99120 tablets
- MSM per serving
- 1,500 mgin 1 tablet
- Pack lasts
- 120 daysif you take 1 tablet (1,500 mg) a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 24
Doctor's Best
MSM with OptiMSM 1,500 mg
Tablets
80Good qualityCountry not stated7.8¢per 1,000 mg
142% more
- Pack
- $13.99120 tablets
- MSM per serving
- 1,500 mgin 1 tablet
- Pack lasts
- 120 daysif you take 1 tablet (1,500 mg) a day
drbvitamins.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 25
Nutricost
MSM Tablets
Tablets
80Good qualityCountry not stated8.3¢per 1,000 mg
160% more
- Pack
- $19.97240 tablets120 servings
- MSM per serving
- 2,000 mgin 2 tablets
- Pack lasts
- 240 daysif you take 1 tablet (1,000 mg) a day
nutricost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 26
Amazing Nutrition
Amazing Formulas MSM (Methylsulfonylmethane)
Capsules
85Good qualityMade in USA8.3¢per 1,000 mg
160% more
- Pack
- $9.99120 capsules60 servings
- MSM per serving
- 2,000 mgin 2 capsules
- Pack lasts
- 120 daysif you take 1 capsule (1,000 mg) a day
amazingnutrition.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 27
Doctor's Best
MSM
Capsules
80Good qualityCountry not stated8.3¢per 1,000 mg
160% more
- Pack
- $14.99180 capsules60 servings
- MSM per serving
- 3,000 mgin 3 capsules
- Pack lasts
- 180 daysif you take 1 capsule (1,000 mg) a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 28
Doctor's Best
MSM with OptiMSM
Capsules
80Good qualityCountry not stated8.3¢per 1,000 mg
160% more
- Pack
- $14.99180 capsules60 servings
- MSM per serving
- 3,000 mgin 3 capsules
- Pack lasts
- 180 daysif you take 1 capsule (1,000 mg) a day
drbvitamins.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 29
NOW Foods
MSM, 1,000 mg
Capsules
80Good qualityMade in USA8.5¢per 1,000 mg
165% more
- Pack
- $20.36240 capsules120 servings
- MSM per serving
- 2,000 mgin 2 capsules
- Pack lasts
- 240 daysif you take 1 capsule (1,000 mg) a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 30
Swanson Vitamins
MSM
Capsules
80Good qualityCountry not stated9.1¢per 1,000 mg
184% more
- Pack
- $11.39250 capsules125 servings
- MSM per serving
- 1,000 mgin 2 capsules
- Pack lasts
- 125 daysif you take 2 capsules (1,000 mg) a day
swansonvitamins.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 31
Nature's Way
MSM, 1,000 mg
Tablets
80Good qualityPacked in USA9.5¢per 1,000 mg
196% more
- Pack
- $18.99200 tablets
- MSM per serving
- 1,000 mgin 1 tablet
- Pack lasts
- 200 daysif you take 1 tablet (1,000 mg) a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 32
Swanson Vitamins
MSM
Capsules
80Good qualityCountry not stated9.6¢per 1,000 mg
198% more
- Pack
- $11.96250 capsules125 servings
- MSM per serving
- 1,000 mgin 2 capsules
- Pack lasts
- 125 daysif you take 2 capsules (1,000 mg) a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 33
NOW Foods
MSM, Methylsulfonylmethane
Capsules
80Good qualityMade in USA9.7¢per 1,000 mg
202% more
- Pack
- $11.62120 capsules60 servings
- MSM per serving
- 2,000 mgin 2 capsules
- Pack lasts
- 120 daysif you take 1 capsule (1,000 mg) a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 34
Swanson Vitamins
MSM, 1,000 mg
Capsules
80Good qualityCountry not stated9.9¢per 1,000 mg
209% more
- Pack
- $23.79240 capsules
- MSM per serving
- 1,000 mgin 1 capsule
- Pack lasts
- 240 daysif you take 1 capsule (1,000 mg) a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 35
Swanson Vitamins
MSM
Capsules
80Good qualityCountry not stated9.9¢per 1,000 mg
209% more
- Pack
- $23.79240 capsules
- MSM per serving
- 1,000 mgin 1 capsule
- Pack lasts
- 240 daysif you take 1 capsule (1,000 mg) a day
swansonvitamins.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 36
BulkSupplements
MSM (Methylsulfonylmethane) Capsules
Capsules
80Good qualityMade in USA$0.10per 1,000 mg
211% more
- Pack
- $17.97240 capsules60 servings
- MSM per serving
- 3,000 mgin 4 capsules
- Pack lasts
- 120 daysif you take 2 capsules (1,500 mg) a day
bulksupplements.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 37
Bluebonnet Nutrition
MSM Powder
Powder
80Good qualityMade in USA$0.10per 1,000 mg
215% more
- Pack
- $22.95227 g (8 oz)87 servings
- MSM per serving
- 2,600 mgin 2.6 g
- Pack lasts
- 227 daysif you take 1,000 mg a day
bluebonnetnutrition.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 38
Life Extension
MSM
Capsules
80Good qualityCountry not stated$0.11per 1,000 mg
227% more
- Pack
- $10.50100 capsules33 servings
- MSM per serving
- 3,000 mgin 3 capsules
- Pack lasts
- 100 daysif you take 1 capsule (1,000 mg) a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 39
Natural Factors
MSM, 1,000 mg
Tablets
85Good qualityMade in Canada$0.11per 1,000 mg
249% more
- Pack
- $10.0690 tablets
- MSM per serving
- 1,000 mgin 1 tablet
- Pack lasts
- 90 daysif you take 1 tablet (1,000 mg) a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 40
Swanson Vitamins
MSM, 1,000 mg
Capsules
80Good qualityCountry not stated$0.11per 1,000 mg
251% more
- Pack
- $13.49120 capsules
- MSM per serving
- 1,000 mgin 1 capsule
- Pack lasts
- 120 daysif you take 1 capsule (1,000 mg) a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
Good to know
- Fact
- 1,660%more per 1,000 mg for the most expensive product than for the cheapest.
- Fact
- 1,660%more per 1,000 mg for the cheapest liquid than for the cheapest powder.
How we checked: one-time price for each size in the store’s US online shop, before sales tax and shipping, without subscriptions or coupons. Prices change often, so check the store before you buy. More on how we check
The amount we compare by only makes products comparable – it is not a dosage recommendation. Not medical advice.
How we calculate
Cost per dose = price ÷ (servings × amount per serving) × comparison amount. Example: $119.99 for 74 servings with 24 g of protein each is 1,776 g of protein. $119.99 ÷ 1,776 g × 30 g = $2.03 per 30 g of protein.
Found a mistake or a product we should add? Email us