Amino acids
L-lysine
An essential amino acid from meat, fish, dairy and beans. Your body needs it to build protein and to make collagen and carnitine.
78 products from US online stores, sorted by what 1,000 mg of lysine costs – not by the price per pack.
2.2¢Lowest cost
per 1,000 mg lysine
- Prices checked Nov 1, 2026, US
- No paid placements
What does 1,000 mg mean?
- lysine per serving in most of the products we checked
- 500–1,000 mglysine per serving in most of the products we checked
- 1,000 mg is about one serving: half of the 78 products we checked have up to 960 mg per serving, the other half more.
- There’s no official daily amount for lysine.
We compare by 1,000 mg only so products line up – it’s not a recommendation. Not medical advice.
Where products miss quality points
How the 78 products score
- Very good 90+: 1
- Good 75+: 73
- Fair 60+: 1
- Low under 60: 3
3 products contain titanium dioxide – a food authority has banned, restricted or flagged it as a possible health risk. Their score is cut in half, so it’s always in the red range. Each product says why.
- have no seal from an independent testing program
- 99%have no seal from an independent testing program10 of 30 testing points for GMP, 15 for the 15 whose label says “third-party tested”
The full 30 testing points need an independent test. Every supplement sold in the US is made under the FDA’s GMP rules – the maker checks its own products, which gives 10 points. A seal from a testing program like NSF, USP or Informed Choice means a lab outside the company checks that what’s inside matches the label. Most brands don’t take part. That doesn’t make a product bad – without a seal, a clean product still gets up to 80.
We find seals on the label and in NSF’s public lists. USP and Informed Choice don’t let us search their lists automatically, so a seal that’s only in their lists can be missing. How the score works
Pack size
Compare packs of a similar size.
All sizes in one list can affect the results – big packs usually cost less per 1,000 mg. Pick a size above to compare packs that are alike.
78 products · cheapest per 1,000 mg lysine first
- Rank 1
Nutricost
L-Lysine, Unflavored
Powder
85Good qualityPacked in USA2.2¢per 1,000 mg
Lowest
- Pack
- $21.951 kg (2.2 lb)1,000 servings
- Lysine per serving
- 1,000 mgin 1 g
- Pack lasts
- 1,000 daysif you take 1,000 mg a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 2
Nutricost
L-Lysine Powder
Powder
85Good qualityMade in USA2.5¢per 1,000 mg
15% more
- Pack
- $24.97992 g (2.2 lb)992 servings
- Lysine per serving
- 1,000 mgin 1 g
- Pack lasts
- 992 daysif you take 1,000 mg a day
nutricost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 3
BulkSupplements
L-Lysine HCl Powder
Powder
80Good qualityCountry not stated2.8¢per 1,000 mg
27% more
- Pack
- $27.971,000 servings
- Lysine per serving
- 1,000 mg
- Pack lasts
- 1,000 daysif you take 1,000 mg a day
bulksupplements.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 4
Best Naturals
L-Lysine Powder
Powder
80Good qualityMade in USA3.1¢per 1,000 mg
40% more
- Pack
- $13.99822 servings
- Lysine per serving
- 552 mg
- Pack lasts
- 453 daysif you take 1,000 mg a day
shopbestnaturals.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 5
Nutricost
L-Lysine, Unflavored
Powder
85Good qualityMade in USA3.2¢per 1,000 mg
45% more
- Pack
- $15.95500 g (1.1 lb)500 servings
- Lysine per serving
- 1,000 mgin 1 g
- Pack lasts
- 500 daysif you take 1,000 mg a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 6
Nutricost
L-Lysine Powder
Powder
85Good qualityCountry not stated3.6¢per 1,000 mg
64% more
- Pack
- $17.97499 g (1.1 lb)499 servings
- Lysine per serving
- 1,000 mgin 1 g
- Pack lasts
- 499 daysif you take 1,000 mg a day
nutricost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 7
NutraBio
Lysine Powder
Powder
70Fair qualityMade in USA4.4¢per 1,000 mg
101% more
- Pack
- $21.99499 g (1.1 lb)499 servings
- Lysine per serving
- 1,000 mgin 1 g
- Pack lasts
- 499 daysif you take 1,000 mg a day
nutrabio.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 8
NOW Foods
L-Lysine Pure Powder
Powder
80Good qualityCountry not stated4.5¢per 1,000 mg
103% more
- Pack
- $15.92822 servings
- Lysine per serving
- 435 mg
- Pack lasts
- 357 daysif you take 1,000 mg a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 9
BulkSupplements
L-Lysine HCl Powder
Powder
80Good qualityCountry not stated4.6¢per 1,000 mg
109% more
- Pack
- $22.97500 servings
- Lysine per serving
- 1,000 mg
- Pack lasts
- 500 daysif you take 1,000 mg a day
bulksupplements.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 10
Nature's Life
L-Lysine HCI Powder, 435 mg
Powder
80Good qualityCountry not stated5.8¢per 1,000 mg
163% more
- Pack
- $11.54460 servings
- Lysine per serving
- 435 mg
- Pack lasts
- 200 daysif you take 1,000 mg a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 11
NOW Foods
L-Lysine, 1,000 mg
Tablets
80Good qualityMade in USA6.9¢per 1,000 mg
215% more
- Pack
- $17.30250 tablets
- Lysine per serving
- 1,000 mgin 1 tablet
- Pack lasts
- 250 daysif you take 1 tablet (1,000 mg) a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 12
Amazing Nutrition
Amazing Formulas L-Lysine - 1000 Mg
Tablets
80Good qualityMade in USA6.9¢per 1,000 mg
216% more
- Pack
- $24.99360 tablets
- Lysine per serving
- 1,000 mgin 1 tablet
- Pack lasts
- 360 daysif you take 1 tablet (1,000 mg) a day
amazingnutrition.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 13
Best Naturals
L-Lysine 1000 mg
Tablets
80Good qualityMade in USA7.2¢per 1,000 mg
229% more
- Pack
- $12.99180 tablets
- Lysine per serving
- 1,000 mgin 1 tablet
- Pack lasts
- 180 daysif you take 1 tablet (1,000 mg) a day
shopbestnaturals.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 14
Source Naturals
L-Lysine
Powder
80Good qualityCountry not stated7.6¢per 1,000 mg
244% more
- Pack
- $7.5073 servings
- Lysine per serving
- 1,360 mg
- Pack lasts
- 99 daysif you take 1,000 mg a day
sourcenaturals.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 15
21st Century
L-Lysine, 1,000 mg
Tablets
30Low qualityCountry not stated7.8¢per 1,000 mg
254% more
- Pack
- $6.9990 tablets
- Lysine per serving
- 1,000 mgin 1 tablet
- Pack lasts
- 90 daysif you take 1 tablet (1,000 mg) a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 16
21st Century
L-Lysine 1000 mg
Tablets
30Low qualityCountry not stated7.8¢per 1,000 mg
254% more
- Pack
- $6.9990 tablets
- Lysine per serving
- 1,000 mgin 1 tablet
- Pack lasts
- 90 daysif you take 1 tablet (1,000 mg) a day
21stcenturyvitamins.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 17
Nutricost
L-Lysine, 1,000 mg
Tablets
85Good qualityCountry not stated8.3¢per 1,000 mg
279% more
- Pack
- $19.95240 tablets
- Lysine per serving
- 1,000 mgin 1 tablet
- Pack lasts
- 240 daysif you take 1 tablet (1,000 mg) a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 18
Amazing Nutrition
Amazing Formulas L-Lysine - 1000 Mg
Tablets
80Good qualityMade in USA8.3¢per 1,000 mg
279% more
- Pack
- $14.99180 tablets
- Lysine per serving
- 1,000 mgin 1 tablet
- Pack lasts
- 180 daysif you take 1 tablet (1,000 mg) a day
amazingnutrition.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 19
BulkSupplements
L-Lysine HCl Powder
Powder
80Good qualityCountry not stated8.4¢per 1,000 mg
283% more
- Pack
- $20.97333 servings
- Lysine per serving
- 750 mg
- Pack lasts
- 249 daysif you take 1,000 mg a day
bulksupplements.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 20
Nutricost
L-Lysine
Capsules
85Good qualityMade in USA8.8¢per 1,000 mg
300% more
- Pack
- $21.95500 capsules250 servings
- Lysine per serving
- 1,000 mgin 2 capsules
- Pack lasts
- 250 daysif you take 2 capsules (1,000 mg) a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 21
Amazing Nutrition
Amazing Formulas L-Lysine - 500 Mg
Capsules
80Good qualityMade in USA8.8¢per 1,000 mg
301% more
- Pack
- $21.99500 capsules
- Lysine per serving
- 500 mgin 1 capsule
- Pack lasts
- 250 daysif you take 2 capsules (1,000 mg) a day
amazingnutrition.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 22
Source Naturals
L-Lysine, 1,000 mg
Tablets
80Good qualityCountry not stated8.8¢per 1,000 mg
302% more
- Pack
- $17.63200 tablets
- Lysine per serving
- 1,000 mgin 1 tablet
- Pack lasts
- 200 daysif you take 1 tablet (1,000 mg) a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 23
Nutricost
L-Lysine Tablets
Tablets
80Good qualityCountry not stated9.2¢per 1,000 mg
317% more
- Pack
- $21.97240 tablets
- Lysine per serving
- 1,000 mgin 1 tablet
- Pack lasts
- 240 daysif you take 1 tablet (1,000 mg) a day
nutricost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 24
Solgar
L-Lysine, Free Form, 1,000 mg
Tablets
80Good qualityCountry not stated9.2¢per 1,000 mg
319% more
- Pack
- $23.01250 tablets
- Lysine per serving
- 1,000 mgin 1 tablet
- Pack lasts
- 250 daysif you take 1 tablet (1,000 mg) a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 25
Source Naturals
L-Lysine, 1,000 mg
Tablets
80Good qualityCountry not stated9.7¢per 1,000 mg
340% more
- Pack
- $9.66100 tablets
- Lysine per serving
- 1,000 mgin 1 tablet
- Pack lasts
- 100 daysif you take 1 tablet (1,000 mg) a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 26
Nutricost
L-Lysine Capsules
Capsules
85Good qualityMade in USA$0.10per 1,000 mg
355% more
- Pack
- $24.97500 capsules250 servings
- Lysine per serving
- 1,000 mgin 2 capsules
- Pack lasts
- 250 daysif you take 2 capsules (1,000 mg) a day
nutricost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 27
Vitamatic
L-Lysine 500mg
Capsules
80Good qualityCountry not stated$0.10per 1,000 mg
355% more
- Pack
- $17.99360 capsules
- Lysine per serving
- 500 mgin 1 capsule
- Pack lasts
- 180 daysif you take 2 capsules (1,000 mg) a day
vitamaticusa.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 28
Best Naturals
L-Lysine 500 mg
Tablets
80Good qualityMade in USA$0.10per 1,000 mg
373% more
- Pack
- $12.99250 tablets
- Lysine per serving
- 500 mgin 1 tablet
- Pack lasts
- 125 daysif you take 2 tablets (1,000 mg) a day
shopbestnaturals.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 29
Carlson
L-Lysine Powder
Powder
80Good qualityCountry not stated$0.11per 1,000 mg
379% more
- Pack
- $8.42100 g (3.5 oz)83 servings
- Lysine per serving
- 960 mgin 1.2 g
- Pack lasts
- 80 daysif you take 1,000 mg a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 30
Solgar
L-Lysine, Free Form, 1,000 mg
Tablets
80Good qualityCountry not stated$0.11per 1,000 mg
410% more
- Pack
- $11.19100 tablets
- Lysine per serving
- 1,000 mgin 1 tablet
- Pack lasts
- 100 daysif you take 1 tablet (1,000 mg) a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 31
NOW Foods
L-Lysine, 500 mg
Tablets
80Good qualityMade in USA$0.11per 1,000 mg
420% more
- Pack
- $14.28250 tablets
- Lysine per serving
- 500 mgin 1 tablet
- Pack lasts
- 125 daysif you take 2 tablets (1,000 mg) a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 32
NOW Foods
L-Lysine, 1,000 mg
Tablets
80Good qualityMade in USA$0.11per 1,000 mg
421% more
- Pack
- $11.44100 tablets
- Lysine per serving
- 1,000 mgin 1 tablet
- Pack lasts
- 100 daysif you take 1 tablet (1,000 mg) a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 33
Mason Natural
L-Lysine
Tablets
80Good qualityMade in USA$0.12per 1,000 mg
433% more
- Pack
- $5.85100 tablets
- Lysine per serving
- 500 mgin 1 tablet
- Pack lasts
- 50 daysif you take 2 tablets (1,000 mg) a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 34
Nutricost
L-Lysine
Capsules
85Good qualityMade in USA$0.12per 1,000 mg
445% more
- Pack
- $14.95250 capsules125 servings
- Lysine per serving
- 1,000 mgin 2 capsules
- Pack lasts
- 125 daysif you take 2 capsules (1,000 mg) a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 35
NOW Foods
L-Lysine, 500 mg
Tablets
80Good qualityMade in USA$0.12per 1,000 mg
446% more
- Pack
- $5.99100 tablets
- Lysine per serving
- 500 mgin 1 tablet
- Pack lasts
- 50 daysif you take 2 tablets (1,000 mg) a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 36
Amazing Nutrition
Amazing Formulas L-Lysine - 500 Mg
Capsules
80Good qualityMade in USA$0.12per 1,000 mg
446% more
- Pack
- $14.99250 capsules
- Lysine per serving
- 500 mgin 1 capsule
- Pack lasts
- 125 daysif you take 2 capsules (1,000 mg) a day
amazingnutrition.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 37
Swanson Vitamins
L-Lysine, 500 mg
Capsules
80Good qualityCountry not stated$0.12per 1,000 mg
452% more
- Pack
- $18.19300 capsules
- Lysine per serving
- 500 mgin 1 capsule
- Pack lasts
- 150 daysif you take 2 capsules (1,000 mg) a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 38
Swanson Vitamins
L-Lysine - Free Form
Capsules
80Good qualityCountry not stated$0.12per 1,000 mg
452% more
- Pack
- $18.19300 capsules
- Lysine per serving
- 500 mgin 1 capsule
- Pack lasts
- 150 daysif you take 2 capsules (1,000 mg) a day
swansonvitamins.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 39
Carlson
L-Lysine Powder
Powder
80Good qualityCountry not stated$0.12per 1,000 mg
464% more
- Pack
- $9.90100 g (3.5 oz)83 servings
- Lysine per serving
- 960 mgin 1.2 g
- Pack lasts
- 80 daysif you take 1,000 mg a day
carlsonlabs.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 40
Nutricost
L-Lysine, 1,000 mg
Tablets
85Good qualityPacked in USA$0.12per 1,000 mg
468% more
- Pack
- $14.95120 tablets
- Lysine per serving
- 1,000 mgin 1 tablet
- Pack lasts
- 120 daysif you take 1 tablet (1,000 mg) a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
Good to know
- Fact
- 2,442%more per 1,000 mg for the most expensive product than for the cheapest.
- Fact
- 300%more per 1,000 mg for the cheapest capsules than for the cheapest powder.
How we checked: one-time price for each size in the store’s US online shop, before sales tax and shipping, without subscriptions or coupons. Prices change often, so check the store before you buy. More on how we check
The amount we compare by only makes products comparable – it is not a dosage recommendation. Not medical advice.
How we calculate
Cost per dose = price ÷ (servings × amount per serving) × comparison amount. Example: $119.99 for 74 servings with 24 g of protein each is 1,776 g of protein. $119.99 ÷ 1,776 g × 30 g = $2.03 per 30 g of protein.
Found a mistake or a product we should add? Email us