Other compounds
Butyrate
A fatty acid that gut bacteria make from fiber. The cells lining the gut use it as their main fuel.
10 products from US online stores, sorted by what 300 mg of butyrate costs – not by the price per pack.
6.7¢Lowest cost
per 300 mg butyrate
- Prices checked Nov 1, 2026, US
- No paid placements

What does 300 mg mean?
- butyrate per serving in most of the products we checked
- 300–1,500 mgbutyrate per serving in most of the products we checked
- 300 mg is a fixed amount to compare by: half of the 10 products we checked have up to 1,000 mg per serving, the other half more.
- There’s no official daily amount for butyrate.
We compare by 300 mg only so products line up – it’s not a recommendation. Not medical advice.
Where products miss quality points
How the 10 products score
- Very good 90+: 0
- Good 75+: 10
- Fair 60+: 0
- Low under 60: 0
- have no seal from an independent testing program
- 10 of 10have no seal from an independent testing program10 of 30 testing points for GMP, 15 for the 1 whose label says “third-party tested”
The full 30 testing points need an independent test. Every supplement sold in the US is made under the FDA’s GMP rules – the maker checks its own products, which gives 10 points. A seal from a testing program like NSF, USP or Informed Choice means a lab outside the company checks that what’s inside matches the label. Most brands don’t take part. That doesn’t make a product bad – without a seal, a clean product still gets up to 80.
We find seals on the label and in NSF’s public lists. USP and Informed Choice don’t let us search their lists automatically, so a seal that’s only in their lists can be missing. How the score works
Pack size
Compare packs of a similar size.
All sizes in one list can affect the results – big packs usually cost less per 300 mg. Pick a size above to compare packs that are alike.
10 products · cheapest per 300 mg butyrate first
- Rank 1
Nutricost
Sodium Butyrate
Capsules
80Good qualityCountry not stated6.7¢per 300 mg
Lowest
- Pack
- $19.97120 capsules60 servings
- Butyrate per serving
- 1,500 mgin 2 capsules
- Pack lasts
- 120 daysif you take 1 capsule (750 mg) a day
nutricost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 2
Absolute Nutrition
Sodium Butyrate
Capsules
80Good qualityCountry not stated$0.13per 300 mg
91% more
- Pack
- $25.44120 capsules60 servings
- Butyrate per serving
- 1,000 mgin 2 capsules
- Pack lasts
- 120 daysif you take 1 capsule (500 mg) a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 3
Deva
Vegan Tributyrin, 500 mg
Capsules
80Good qualityCountry not stated$0.15per 300 mg
119% more
- Pack
- $21.8890 capsules
- Butyrate per serving
- 500 mgin 1 capsule
- Pack lasts
- 90 daysif you take 1 capsule (500 mg) a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 4
Absolute Nutrition
Sodium Butyrate
Capsules
80Good qualityCountry not stated$0.16per 300 mg
145% more
- Pack
- $16.3460 capsules30 servings
- Butyrate per serving
- 1,000 mgin 2 capsules
- Pack lasts
- 60 daysif you take 1 capsule (500 mg) a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 5
BodyBio
Sodium Butyrate
Capsules
80Good qualityCountry not stated$0.18per 300 mg
178% more
- Pack
- $36.99100 capsules50 servings
- Butyrate per serving
- 1,200 mgin 2 capsules
- Pack lasts
- 100 daysif you take 1 capsule (600 mg) a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 6
BodyBio
Sodium Butyrate
Capsules
80Good qualityCountry not stated$0.22per 300 mg
238% more
- Pack
- $26.9960 capsules30 servings
- Butyrate per serving
- 1,200 mgin 2 capsules
- Pack lasts
- 60 daysif you take 1 capsule (600 mg) a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 7
Vitamatic
Clostridium Butyricum
Capsules
80Good qualityMade in USA$0.31per 300 mg
373% more
- Pack
- $24.9960 capsules
- Butyrate per serving
- 397 mgin 1 capsule
- Pack lasts
- 60 daysif you take 1 capsule (397 mg) a day
vitamaticusa.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 8
Doctor's Best
Postbiotic Butyrate, High Absorption
Capsules
80Good qualityCountry not stated$0.77per 300 mg
1,051% more
- Pack
- $22.9930 capsules
- Butyrate per serving
- 300 mgin 1 capsule
- Pack lasts
- 30 daysif you take 1 capsule (300 mg) a day
vitacost.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 9
Doctor's Best
High Absorption Postbiotic Butyrate 300 mg
Capsules
80Good qualityCountry not stated$0.77per 300 mg
1,051% more
- Pack
- $22.9930 capsules
- Butyrate per serving
- 300 mgin 1 capsule
- Pack lasts
- 30 daysif you take 1 capsule (300 mg) a day
drbvitamins.com (opens in a new tab)Checked Nov 1, 2026 · Label
- Rank 10
Natural Factors
Sodium Butyrate Postbiotic
Softgels
85Good qualityCountry not stated$1.00per 300 mg
1,401% more
- Pack
- $49.9560 softgels30 servings
- Butyrate per serving
- 500 mgin 2 softgels
- Pack lasts
- 30 daysif you take 2 softgels (500 mg) a day
naturalfactors.com (opens in a new tab)Checked Nov 1, 2026 · Label
Good to know
- Fact
- 1,401%more per 300 mg for the most expensive product than for the cheapest.
- Fact
- 1,401%more per 300 mg for the cheapest softgels than for the cheapest capsules.
How we checked: one-time price for each size in the store’s US online shop, before sales tax and shipping, without subscriptions or coupons. Prices change often, so check the store before you buy. More on how we check
The amount we compare by only makes products comparable – it is not a dosage recommendation. Not medical advice.
How we calculate
Cost per dose = price ÷ (servings × amount per serving) × comparison amount. Example: $119.99 for 74 servings with 24 g of protein each is 1,776 g of protein. $119.99 ÷ 1,776 g × 30 g = $2.03 per 30 g of protein.
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